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Rabbit anti-STUB1/CHIP Antibody, Affinity Purified

品牌
Sigma-Aldrich
货号
PLA0196
规格纯度
Powered by Bethyl Laboratories, Inc.
参考价格
5699.93 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

The epitope recognized by PLA0196 maps to a region between residue 1 and 50 of human STIP1 homology and U-box containing protein 1 (carboxy terminus of Hsp70-interacting protein) using the numbering given in entry NP_005852.2 (GeneID 10273).

外形

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他说明

STUB1/CHIP is an E3 ubiquitin ligase and co-chaperone of heat-shock protein 70 (Hsp70). STUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimer′s and Down′s syndrome patients. STUB1/CHIP has been reported to also have intrinsic chaperone activity and recognize non-native proteins in response to heat stress. In this way, STUB1/CHIP has been shown to be a direct chaperone for p53.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity purified immunoglobulin
antibody product typeprimary antibodies
等级Powered by Bethyl Laboratories, Inc.
species reactivitymouse, human
technique(s)immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000
登记号NP_005852.2
运输wet ice
储存温度2-8℃
Gene Informationrabbit ... STUB1/CHIP(10273)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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