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Rabbit anti-FOXO1a Antibody, Affinity Purified

品牌
Sigma-Aldrich
货号
PLA0084
规格纯度
Powered by Bethyl Laboratories, Inc.
参考价格
5699.93 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

The epitope recognized by PLA0084 maps to a region between residues 600 and the C-terminus (residue 652) of human Forkhead Box O1a using the numbering given in Swiss-Prot entry Q12778 (GeneID 2308).

外形

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

其他说明

Forkhead box protein 01A (FOXO1a) belongs to a large family of Forkhead proteins that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). FOXO1 is a transcription factor that integrates cell signals to mediate metabolism, the cell cycle, DNA repair, and response to cellular stress. In response to insulin, FOXO1 is phosphorylated by Akt and excluded from the nucleus and subsequently degraded. Over-expressed cytoplasmic FOXO1 interacts with TSC2 to cause its degradation and subsequent activation of the mTOR pathway; while nuclear localization inhibits the mTOR pathway.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity purified immunoglobulin
antibody product typeprimary antibodies
等级Powered by Bethyl Laboratories, Inc.
species reactivityhuman
technique(s)immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000-1:10,000
登记号Q12778
运输wet ice
储存温度2-8℃
Gene Informationrabbit ... FOXO1a(2308)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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