位置:首页 > 品牌 > Sigma-Aldrich >

PCSK9 murine

品牌
Sigma-Aldrich
货号
SRP6286
规格纯度
recombinant, expressed in HEK 293 cells, ≥97% (SDS-PAGE)
参考价格
5803.04 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

外形

Sterile filtered through a 0.22 micron filter. Lyophilized from 1 x PBS, pH 7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 100 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRESNA.32

产品性质

生物来源mouse
重组expressed in HEK 293 cells
标签6-His tagged (N-terminus)
测定≥97% (SDS-PAGE)
形式lyophilized powder
分子量calculated mol wt 72 kDa
observed mol wt 20 kDa (DTT-reduced. Protein migrates due to glycosylation. Gln 35 is the predicted N-terminus .)
observed mol wt 64 kDa
包装pkg of 20 μg
杂质<1 EU/μg endotoxin (LAL test)
UniProt登记号Q80W65
运输wet ice
储存温度−20℃
Gene Informationmouse ... PCSK9(100102)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号