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p27KIP1, GST tagged human

品牌
Sigma-Aldrich
CAS
480738-30-5
货号
SRP5109
规格纯度
recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
4386.57 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

KIP1 (cyclin-dependent kinase inhibitor 1B) is a kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation. Many tumorigenic processes modulate cell-cycle progression by regulating the levels of the cyclin-dependent kinase inhibitor KIP1. KIP1 binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4. The phosphorylation- and ubiquitination-dependent proteolysis of KIP1 is implicated in control of the G1-S transition in the cell cycle. KIP1 is critical for retinoblastoma protein (Rb)-induced cellular proliferative senescence.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
分子量 ~52 kDa
NCBI登记号NM_004064
application(s)cell analysis
运输dry ice
储存温度−70℃
Gene Informationhuman ... CDKN1B(1027)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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