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Hexaminolevulinate hydrochloride

品牌
Sigma-Aldrich
CAS
140898-91-5
货号
SML1637
规格纯度
≥98% (HPLC)
参考价格
1117.23 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis.

基本信息

经验(实验)分子式C11H21NO3 · HCl
分子量251.75
MDL编号MFCD03695491
PubChem化学物质编号329825978

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性H2O: 20 mg/mL, clear
储存温度room temp
SMILES stringCCCCCCOC(CCC(CN)=O)=O.[H]Cl
InChI1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H
InChI keyLZYXPFZBAZTOCH-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3

Sigma-Aldrich

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