产品说明
一般描述
Bone morphogentic protein 4 (BMP4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.
Animal free human recombinant BMP4 is a fully active homodimeric protein consisting of two 107 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.
Product Source: E. coli
特异性
Cross Reactivty
Mouse
应用
Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
质量
Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
外形
Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human BMP-4 is manufactured using all non-animal reagents
储存及稳定性
Store at -20°C for up to 6 months from date of receipt.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160405 |
产品性质
| 质量水平 | 100 |
| 重组 | expressed in E. coli |
| 测定 | >98% (SDS-PAGE and HPLC) |
| 杂质 | <0.1 μg/mg protein endotoxin (<1EU/μg) |
| NCBI登记号 | NM_001202.3 NM_130850.2 NM_130851.2 |
| UniProt登记号 | P12644 |
| 运输 | dry ice |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
