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Anti-TRIM5 gamma antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3501191
规格纯度
affinity isolated antibody
参考价格
4802.96 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

TRIM5 gamma Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has five alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. While a function has not yet been assigned to TRIM5gamma, it is known that expression of TRIM5α variants from humans, rhesus monkeys, and African green monkeys enable resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. Furthermore, the TRIM5δ isoform appears to serve as a scaffold for the assembly of endogenous BTBD1 and BTBD2 proteins and also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.

免疫原

TRIM5 gamma antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of human TRIM5 gamma.The immunogen is located within the last 50 amino acids of TRIM5 gamma.

应用

TRIM5 gamma antibody can be used for detection of TRIM5 gamma by Western blot at 2 μg/mL. A band at approximately 35 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 20 μg/mL.Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

外形

Supplied in PBS containing 0.02% sodium azide.

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式liquid
species reactivityhuman
浓度1 mg/mL
technique(s)immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG
NCBI登记号NP_149083
UniProt登记号Q9C035
运输wet ice
储存温度−20℃
Gene Informationhuman ... TRIM5(85363)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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