Anti-TRIP8b Antibody, clone N212A/34

产品说明

一般描述

Tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) is also called PEX5-related protein, PEX5-like protein and Peroxin-5-related protein (Pex5Rp). TRIP8b a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel subunit that is involved in HCN cynclic nucleotide dependence and expression at the cell surface. TRIP8b is expressed specifically in the brain.

特异性

This antibody demonstrates specificity for TRIP8b containing exon 1b. It does not cross react with TRIP8b containing exons 1a, 2, or 4.

免疫原

Recombinant protein corresponding to rat TRIP8b.

应用

Anti-TRIP8b Antibody, clone N212A/34 is a highly specific mouse monoclonal antibody & that targets Tetratricopeptide repeat-containing Rab8b-interacting protein & has been tested in western blotting.
Research Sub Category
Synapse & Synaptic Biology
Research Category
Neuroscience
Western Blotting Analysis: 0.5 μg/mL of this antibody detected TRIP8b in 10 μg of human brain tissue lysate.

Western Blotting Analysis: A representative lot detected TRIP8b in COS cell lysates transiently transfected with GFP tagged TRIP8b (exon1b) and not in COS cell lysates transiently transfected with TRIP8b (exon1a, 2, or 4) or with untagged Kv2.1 plasmid (Prof. J. Trimmer, University of California, Davis.).

质量

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analyis: 0.5 μg/mL of this antibody detected TRIP8b in 10 μg of rat brain tissue lysate.

目标描述

~70 kDa observed. Multiple isoforms may be observed due to alternative splicing (Lewis, A. S., et al. (2009). J Neurosci. 29(19):6250-6265.). Uncharacterized band(s) may be observed in some cell lysates.

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Rat brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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