产品说明
一般描述
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
免疫原
A phospho specific peptide corresponding to residues surrounding S366 of human TMEM173.
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | liquid |
species reactivity | human |
浓度 | 0.76 mg/mL |
technique(s) | western blot: 1:500-1:2000 |
UniProt登记号 | Q86WV6 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... TMEM173(340061) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |