产品说明
一般描述
The SNCA (synuclein α) gene codes for a 140-amino acid protein a-synuclein, that is mapped to human chromosome 4q21-23.
免疫原
The antiserum was produced against synthesized peptide derived from human Synuclein-alpha around the phosphorylation site of Tyr133.
Immunogen Range: 91-140
生化/生理作用
Synuclein-α is known to induce oligodendrocyte maturation. Accumulation of α-synuclein in oligodendrocytes results in the loss of myelin and causes neurodegeneration, leading to multiple system atrophy. Mutations in the SNCA gene results in Parkinson′s disease.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen 14 kDa |
species reactivity | mouse, rat, human |
浓度 | ~1 mg/mL |
technique(s) | ELISA: 1:40000 western blot: 1:500-1:1000 |
NCBI登记号 | P37840 |
UniProt登记号 | P37840 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... SNCA(6622) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |