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Anti-Phospho-MLKL-S441 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701929
包装型号
规格纯度
参考价格
5406.77 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.

免疫原

A phospho synthetic peptide corresponding to residues surrounding S441 of Mouse MLKL.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆polyclonal
形式liquid
species reactivityrat
浓度0.238 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt登记号Q9D2Y4
运输wet ice
储存温度−20℃
Gene Informationmouse ... MLKL(74568)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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