产品说明
一般描述
Oligodendrocyte transcription factor 2 (UniProt Q9EQW6; also known as bHLHe19, Olig-2, Oligo2, RACK17, RK17) is encoded by the Olig2 (also known as Bhlhb1) gene (Gene ID 50913) in murine species. Olig2 is a basic helix-loop-helix (bHLH) transcription factor expressed in a spinal cord ventricular zone domain where it mediates the sequential generation of motoneurons and oligodendrocytes during embryogenesis. Olig2 also functions as an anti-neurogenic factor in pMN progenitors at early time points to sustain the cycling progenitor pool. The anti-neurogenicity of Olig2 is also responsible for its role in tumorigenesis, especially in brain tumors and leukemia. Due to its expression in glioblastoma and other diffuse gliomas, Olig2 is a useful diagnostic marker of these brain tumors.
特异性
The unconjugated antibody (Cat. No. AB9610) recognizes the ~32 kDa Olig-2 protein by Western blotting.
免疫原
Recombinant mouse Olig-2.
应用
Research Sub Category
Transcription Factors
The unconjugated antibody (Cat. No. AB9610) is shown to be suitable also for Western blotting, immunocytochemistry, immunohistochemistry, and immunoprecipitation applications.
Research Category
Neuroscience
Anti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate is an antibody against Olig-2 for use in Immunofluorescence.
质量
Evaluated by Immunofluorescence in mouse brain tissue.
Immunofluorescence Analysis: A 1:50-100 dilution of this antibody detected Olig-2 in mouse brain tissue sections.
目标描述
~32 kDa observed.
外形
Ammonium Sulfate
Purified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
法律信息
ALEXA FLUOR is a registered trademark of Life Technologies
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | ALEXA FLUOR® 488 |
| 抗体形式 | purified antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| species reactivity | mouse, human, rat |
| technique(s) | immunofluorescence: suitable |
| NCBI登记号 | NM_016967.2 |
| UniProt登记号 | Q9EQW6 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
