产品说明
一般描述
Myosin Light Chain Kinase (MLCK) also known as MYLK is a Ca2+/calmodulin dependent myosin light chain phosphorylating agent. This enzyme plays a major role in the phosphorylation of the regulatory light chains of myosin which are essential for the shortening and tension development of smooth muscle cells resulting in smooth muscle contraction. Myosin light chain kinase are widely expressed in many different tissues and cells of eukaryote species. There are two genes mylk1 and mylk2 encoding the MLCK protein, mylk2 is exclusively expressed in skeletal muscle cells.
免疫原
Purified chicken gizzard myosin light chain kinase.
应用
Monoclonal Anti-Myosin Light Chain Kinase recognizes the myosin light chain kinase of smooth muscle and from non-muscle cells such as cultured fibroblasts. Reactivity has been observed with myosin light chain kinase from chicken, turkey, bovine, human, mouseand pig origin. The antibody is recommended to use in various immunological techniques, including Immunoblotting (~160kDa), Immunohistochemistry and immunofluorescence.
外形
Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.
其他说明
This product is for R&D use only, not for drug, household, or other uses.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | mouse |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | K36, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~160 kDa |
| species reactivity | turkey, bovine, pig, mouse, chicken, human |
| 包装 | antibody small pack of 25 μL |
| 浓度 | ~1 mg/mL |
| technique(s) | immunoblotting: 0.25-0.5 μg/mL using chicken gizzard extract |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | Q15746 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
