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Anti-MEK3 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701436
包装型号
规格纯度
参考价格
4266.29 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]

免疫原

A synthesized peptide derived from human MEK3

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivityhuman, rat, mouse
浓度1.3 mg/mL
technique(s)immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号P46734
运输wet ice
储存温度−20℃
Gene Informationhuman ... MAP2K3(5606)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

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