产品说明
一般描述
Importin 4 is a member of importin protein family. It is a 119 kDa protein.
免疫原
synthetic peptide corresponding to a sequence at the N-terminal of human Importin 4
应用
Anti-Importin 4 (N-terminal) antibody produced in rabbit has been used in several immunochemical techniques including immunoblotting, immunoprecipitation and immunofluorescence.
生化/生理作用
Importins can mediate the nuclear import of a diverse set of protein or RNA cargoes. Importins were implicated in anti-aggregation activity of highly basic cargo like histones and ribosomal proteins and in preventing their undesired interactions with other cellular components. It has been identified as an import factor for ribosomal protein rpS3a, the vitamin D receptor (VDR) and the sperm transition protein transition protein 2 (TP2).
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~120 kDa |
| species reactivity | human |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunoprecipitation (IP): 2.5-5.0 μg using HepG2 cell lysates indirect immunofluorescence: 1.25-2.5 μg/mL using HEK-293T cells overexpressing human Importin 4 western blot: 1-2 μg/mL using HepG2 cell lysates |
| UniProt登记号 | Q8TEX9 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IPO4(79711) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
