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Anti-FANCA Antibody, clone 5G9

品牌
Sigma-Aldrich
货号
MABC557
规格纯度
clone 5G9, from mouse
参考价格
6022.61 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

FANCA, also named as FAA, FACA and FANCH, belongs to the multisubunit FA complex which is not found in patients with Fanconi anemia. FANCA may be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Mutations in FANCA have been associated with Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies.

免疫原

KLH-conjugated linear peptide corresponding to the C-terminus of human FANCA.

应用

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected FANCA in 10 µg of HeLa cell lysate.

Western Blotting Analysis: A representative lot from an independent laboratory detected FANCA in normal HSC93 and FA mutant lymphoblast whole cell extracts. The same lot also detected FANCA in HeLa whole cell extracts and in FANCA transfected PD430 whole cell extracts (Tremblay, C. S., et al. (2008). Blood. 112(5):2062-2070.).

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated FANCA from yeast extracts expressing FANCA. The same lot also immunoprecipiated FANCA from 293T whole cell extracts expressing FANCA (Tremblay, C. S., et al. (2008). Blood. 112(5):2062-2070.)

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated FANCA from FANCA wild type FA lymphoblast cell lysate (de Winter, J. P., et al. (2000). Hum Mol Genet. 9(18):2665-2674.).
Anti-FANCA Antibody, clone 5G9 is a highly specific mouse monoclonal antibody, that targets FANCA & has been tested in western blotting & IP.

质量

Evaluated by Western Blotting in Raji cell lysates.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FANCA in 10 µg of Raji cell lysate.

目标描述

~165 kDa observed

外形

Protein G Purified
Format: Purified

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆5G9, monoclonal
species reactivityhuman
technique(s)immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_000126
UniProt登记号O15360
运输wet ice
Gene Informationhuman ... FANCA(2175)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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