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ANTI-CD45(C-TERMINAL) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1306481
规格纯度
IgG fraction of antiserum, buffered aqueous solution
参考价格
6662.67 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Protein tyrosine phosphatase, receptor type C (PTPRC) or leucocyte common antigen CD45 is expressed on T-cells and is found in multiple isoforms. The extracellular domain of the protein is predicted to have an amino-terminal mucin-like segment, a cysteine-rich domain and three fibronectin type 3 domains. The gene encoding this protein is localized on human chromosome 1q31.3.

应用

ANTI-CD45(C-TERMINAL) antibody produced in rabbit has been used in Western blotting.

生化/生理作用

Protein tyrosine phosphatase, receptor type C (PTPRC) or leucocyte common antigen CD45 acts as a protein tyrosine phosphatase in leucocyte signaling. It has a role in flow cytometric diagnostics in leukemia. By dephosphorylation of Src kinases, the protein acts as a regulator of antigen receptor signaling in T and B cells. As a negative regulator of janus kinases, CD45 inhibits cytokine receptor signaling.

外形

Supplied in PBS with 0.09% (W/V) sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 147254 Da
species reactivityhuman
technique(s)flow cytometry: 1:10-1:50
immunohistochemistry: 1:10-1:50
western blot: 1:1000
NCBI登记号NP_002829.3
UniProt登记号P08575
运输wet ice
储存温度−20℃
Gene Informationhuman ... PTPRC(5788)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

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