产品说明
一般描述
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer.
免疫原
Synthetic peptide directed towards the c-terminal region of Human CASP10
序列
Synthetic peptide located within the following region: QSLCNHLKKLVPRHEDILSILTAVNDDVSRRVDKQGTKKQMPQPAFTLRK
外形
Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
生物来源 | rabbit |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 57 kDa |
species reactivity (predicted by homology) | human |
浓度 | 0.5 mg/mL |
technique(s) | western blot: 1 μg/mL |
NCBI登记号 | NM_032977 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... CASP10(57396) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |