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Anti-Cav1.2 alpha1c, clone 8F9.1 Antibody

品牌
Sigma-Aldrich
货号
MABN863
规格纯度
clone 8F9.1, from mouse
参考价格
5520.38 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Many alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

免疫原

Recombinant protein corresponding to human Cav1.2 alpha1c.

应用

Research Category
Neuroscience
Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected Cav1.2 alpha1c in human cerebellum, human cerebral cortex, and human pancreas tissue.
Anti-Cav1.2 alpha1c, clone 8F9.1 | MABN863 is an antibody against Cav1.2 alpha1c for use in Western Blotting, Immunohistochemistry (Paraffin).
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 5.0 µg/mL of this antibody detected Cav1.2 alpha1c in 10 µg of human brain tissue lysate.

目标描述

~230 kDa observed. UniProt entry Q13936 describes 37 isoforms produced by alternative splicing.

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆8F9.1, monoclonal
species reactivityhuman
technique(s)immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_000710
UniProt登记号Q13936
运输wet ice
Gene Informationhuman ... CACNA1C(775)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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