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Anti-Ly-6G Antibody (mouse), APC, clone 1A8

品牌
Sigma-Aldrich
货号
MABF469
规格纯度
clone 1A8, 0.2 mg/mL, from rat
参考价格
3841.74 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.

免疫原

Immunogen information for this antibody is proprietary information.

应用

This rat monoclonal antibody Anti-Ly-6G (mouse), APC & clone 1A8 validated for use in Flow Cytometry for the detection of Ly-6G.
Research Category
Inflammation & Immunology

质量

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.5 μg of this antibody detected Ly-6G in one million C57Bl/6 bone marrow cells.

外形

Size Exclusion Chromatography
Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.

储存及稳定性

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源rat
偶联物Allophycocyanin conjugate
抗体形式purified antibody
antibody product typeprimary antibodies
克隆1A8, monoclonal
species reactivitymouse
浓度0.2 mg/mL
technique(s)flow cytometry: suitable
同位素/亚型IgG2aκ
UniProt登记号P35461
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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