产品说明
一般描述
Caspase-1 (ICE, interleukin-1b-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1b and IL-18 into active cytokines. Like other caspases, caspase-1 itself is synthesized as a proenzyme that is cleaved during activation into large (20 kDa) and small (10 kDa) subunits.
特异性
AB1871 recognizes the 45 kDa procaspase-1 as well as the 20 kDa cleaved caspase-1.
应用
This Anti-Caspase 1 Antibody is validated for use in IF, IP, WB for the detection of Caspase 1.
Western blot: 1-4 μg/mL
Immunoprecipitation: 4-8 μg/mL
Immunofluorescence: 10-20 μg/mL
Optimal working dilutions must be determined by end user.
外形
Affinity purified immunoglobulin. Liquid in PBS, pH 7.2, containing 50% glycerol, 1% BSA and 0.02% sodium azide.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 纯化方式 | affinity chromatography |
| species reactivity | rat, mouse, human |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunofluorescence: suitable immunoprecipitation (IP): suitable western blot: suitable |
| NCBI登记号 | NM_001223.3 NM_033292.2 NM_033293.2 NM_033294.2 NM_033295.2 |
| UniProt登记号 | P29466 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 2 |
