产品介绍：
产品说明
应用
Wee1, active from rat may be used to study apoptotic signaling.
生化/生理作用
Wee1 is a protein tyrosine kinase that phosphorylates Cdc2 on Tyr15 and hence inactivates the CDK1 and CDK2, which facilitates in the negative regulation of entry of cells into mitosis. Increased level of wee1 stimulates Human Immunodeficiency Virus type 1 (HIV-1) Vpr induced cell cycle arrest at G2/M transition followed by apoptosis.
Protein inhibitor of Cdk2 kinase
单位定义
One unit of Wee 1 is defined as the amount of Wee 1 which inhibits 90% of the activity of 10 units of Cdk2
外形
Solution in 50 mM Tris-HCl, pH 7.5, 1 mM EDTA, 1 mM DTT, 10% Glycerol
基本信息
| MDL编号 | MFCD03459055 |
产品性质
| 质量水平 | 200 |
| 生物来源 | rat |
| 重组 | expressed in E. coli |
| 形式 | solution |
| 分子量 | ~110 kDa |
| UniProt登记号 | Q63802 |
| application(s) | cell analysis |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | rat ... Wee1(308937) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
