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Monoclonal Anti-USP25 antibody produced in mouse

品牌
Sigma-Aldrich
货号
U7883
规格纯度
~1.0 mg/mL, clone U25.7, purified immunoglobulin, buffered aqueous solution
参考价格
4731.57 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Monoclonal Anti-USP25 (mouse IgG2a isotype) is derived from the hybridoma U25.7 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a fragment of human USP25. USP25 (ubiquitin-specific protease 25) is a member of the ubiquitin processing proteases (UBP) family. It is located on the gene-poor region of 21q11.2 human chromosome.

应用

Monoclonal Anti-USP25 antibody has been used in:

  • enzyme linked immunosorbent assay (ELISA)
  • immunoblotting
  • immunocytochemistry

生化/生理作用

USP25 (ubiquitin-specific protease 25) is a target for sumoylation. It takes place within the two ubiquitin interaction motifs (UIM) of USP25 that are required for efficient hydrolysis of Ub (ubiquitin), and thus impairs USP25 activity as a result of reduced affinity to Ub chains. Overexpression of USP25 has been observed in Down syndrome fetal brain.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆U25.7, monoclonal
形式buffered aqueous solution
分子量antigen ~126 kDa
species reactivityhuman, rat, mouse
浓度~1.0 mg/mL
technique(s)immunocytochemistry: suitable
indirect ELISA: suitable
western blot: 1-2 μg/mL using total extract of HEK-293T cells expressing USP25.
同位素/亚型IgG2a
UniProt登记号Q9UHP3
运输dry ice
储存温度−20℃
Gene Informationhuman ... USP25(29761)
mouse ... Usp25(30940)
rat ... Usp25(304150)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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