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Monoclonal Anti-SmB antibody produced in mouse

品牌
Sigma-Aldrich
货号
S0698
规格纯度
~1 mg/mL, clone 12F5, purified immunoglobulin, buffered aqueous solution
参考价格
7967.37 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

SNRPB (small nuclear ribonucleoprotein-associated protein B) is an important constituent of the spliceosome. It codes for SmB/B′ (small nuclear ribonucleoprotein polypeptides B and B1). It is located on human chromosome 20p13. SmB′/B are upregulated in all tissues excluding postnatal brain.
Monoclonal Anti-SmB (mouse IgG1 isotype) is derived from the hybridoma 12F5-H3.D8 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with an SmB recombinant protein.

免疫原

SmB recombinant protein.

应用

  • Monoclonal Anti-SmB antibody produced in mouse has been used in:
  • western blotting
  • enzyme-linked immunosorbent assay (ELISA)
  • immunoprecipitation
  • immunocytochemistry

生化/生理作用

SNRPB (small nuclear ribonucleoprotein-associated protein B) mutations results in cerebro-costo-mandibular syndrome. Downregulation of SNRPB affects the upregulation and processing of RNA splicing machinery components. It also plays a major role in RNA stability.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆12F5, monoclonal
形式buffered aqueous solution
分子量antigen ~25 kDa
species reactivityhuman, mouse, canine
浓度~1 mg/mL
technique(s)immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 0.5-1 μg/mL using HeLa nuclear cell extract
同位素/亚型IgG1
UniProt登记号P14678
运输dry ice
储存温度−20℃
Gene Informationhuman ... SNRPB(6628)
mouse ... Snrpb(20638)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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