产品说明
一般描述
SERCa2 ATPase (sarco/endoplasmic reticulum calcium-ATPase 2) is also known as ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2). It codes for SERCA2a and SERCA2b, that are expressed in all tissues. SERCA2a is highly expressed in heart. SERCa2 is located on human chromosome 12q24.1.
免疫原
canine cardiac sarcoplasmic reticulum vesicles
应用
Anti-SERCa2 ATPase antibody has been used in western blotting and immunocytochemistry.
生化/生理作用
Mutation of SERCa2 ATPase (sarco/endoplasmic reticulum calcium-ATPase 2) or ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) causes Dyskeratosis follicularis. SERCA2a plays a major role in controlling cardiomyocyte Ca2+. ATP2A2 mutation may cause Darier disease (DD).
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD00802883 |
NACRES | NA.41 |
产品性质
质量水平 | 200 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | ascites fluid |
antibody product type | primary antibodies |
克隆 | 2A7-A1, monoclonal |
分子量 | antigen 110 kDa |
包含 | 0.05% sodium azide |
species reactivity | rabbit, canine, guinea pig, mouse, human, rat |
technique(s) | immunoprecipitation (IP): suitable western blot: suitable |
UniProt登记号 | P16615 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... ATP2A2(488) mouse ... Atp2a2(11938) rat ... Atp2a2(29693) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |