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Anti-Peroxiredoxin 3 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
P1247
规格纯度
IgG fraction of antiserum, buffered aqueous solution
参考价格
4330.86 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The PRDX3 gene is located on the human chromosome at 10q26.11.
PRDX3, also known as antioxidant protein 1 (AOP1), MER-5, or SP-22, belongs to a family of proteins termed peroxiredoxins (Prx). It is a mitochondrial protein.

特异性

Whole antiserum is purified to provide an IgG fraction of antiserum Anti-Peroxiredoxin 3 recognizes human PRDX3.

免疫原

synthetic peptide corresponding to amino acids 241-256 of human peroxiredoxin 3, conjugated to KLH via an N-terminal lysine residue.

应用

Anti-Peroxiredoxin 3 antibody produced in rabbit has been used in western blotting.

生化/生理作用

Peroxiredoxin 3 (PRDX3) catalyzes the reduction of peroxides in the presence of thioredoxin. The Prx family has been identified in association with a variety of diverse cellular functions including growth control, proliferation, differentiation, and in the response to oxidative stress. PRDX3 is required to maintain normal mitochondrial function through direct activation by c-Myc, which may explain its overexpression during neoplastic transformation.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

储存及稳定性

For continuous use, store at 2-8 ℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in frost-free freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD06798479
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~25 kDa
species reactivityhuman
technique(s)microarray: suitable
western blot: 1:4,000-1:8,000 using HeLa cell mitochondria extracts
UniProt登记号P30048
运输dry ice
储存温度−20℃
Gene Informationhuman ... PRDX3(10935)

安全信息

储存分类代码11 - Combustible Solids

Sigma-Aldrich

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