产品说明
一般描述
Ceramide, a bioactive sphingolipid belongs to the sphingolipid family of cell lipids. This pore-forming member is insoluble in water. It is a hygroscopic and light sensitive lipid.
应用
C11 TopFluor® Ceramide may be used:
- in the ceramide and B-cell lymphoma-extra-large (Bcl-xL) binding studies to study the effect on ceramide channel formation
- as a tracer in confocal microscopy to treat T84 cells in order to study its localization in sphingomyelinase (SMase)-induced F-actin structures
- to study its effect on the migration of pancreatic cancer stem cells (PCSC) using confocal microscopy
生化/生理作用
Ceramide is known to participate in apoptosis, mediated by mitochondria. Ceramide channels plays a key role in the onset of apoptosis in vivo.
包装
5 mL Amber Glass Screw Cap Vial (810262P-250ug)
法律信息
TopFluor is a registered trademark of Avanti Polar Lipids, Inc.
基本信息
经验(实验)分子式 | C42H70N3O3F2 |
分子量 | 703.02 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 250 μg (810262P-250ug) |
manufacturer/tradename | Avanti Polar Lipids 810262P |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |