产品说明
一般描述
Peripherin is an intermediate filament protein. It is expressed in peripheral and enteric neurons. The gene encoding this protein is localized on rat chromosome 7.
Monoclonal Anti-Peripherin (mouse IgG1 isotype) is derived from the 8G2 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mice immunized with the full-length recombinant rat peripherin. Peripherin was originally identified as a neuronal intermediate filament protein-(IF) is thought to be expressed only in the peripheral nervous system (PNS).
免疫原
full-length recombinant rat peripherin.
应用
Anti-Peripherin antibody, Mouse monoclonal has been used in:
- immunohistochemistry
- western blotting
- enzyme linked immunosorbent assay (ELISA)
- immunofluorescence staining
生化/生理作用
eripherin has been linked with axonal extension and regeneration of nerve fibers. It also has a role in neurite outgrowth propagation. Peripherin is a substrate of protein kinase B/Akt. Phosphorylation of this protein is induced after nerve injury.
Peripherin is upregulated during pheochromocytoma PC12 cell differentiation. Later studies have detected peripherin also in certain central nervous system (CNS) neurons.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01633973 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | 8G2, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | rabbit, mouse, rat, bovine, pig, human, feline |
| technique(s) | immunohistochemistry: suitable indirect ELISA: suitable microarray: suitable western blot: 0.5-1.0 μg/mL using total cell extract from rat PC12 cells |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P41219 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PRPH(5630) mouse ... Prph(19132) rat ... Prph(24688) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
