产品说明
一般描述
The (K+) channel family has been sub-grouped in to 2 TM, 4 TM and 6 TM (K+) channels based on the number of transmembrane domains. The voltage-gated Potassium or (Kv) channels belong to the 6 TM (K+) channel family and are expressed mainly in hematopoietic cells such as T and B lymphocytes, macrophages and natural killer cells. (Kv)1.3 facilitates cell proliferation and can also regulate the immune system. Genetic alterations in (Kv) 1.3 lead to epilepsy, episodic ataxia/myokymia, and episodic cardiac arrhythmia (the long QT syndrome). Anti-potassium channel (Kv) 1.3 (extracellular)−FITC antibody can be used for western blotting of rat brain membranes. Rabbit anti- potassium channel (Kv) 1.3 (extracellular) antibodies reacts specifically with rat and human (Kv) 1.3.
免疫原
synthetic peptide corresponding to residues 211-224 of human KV1.3. Rat and mouse are 12/14 residues identical.
应用
Anti-potassium channel (Kv) 1.3 (extracellular)−FITC antibody can be used in immunoblotting and flow cytometry.
外形
Lyophilized from phosphate buffered saline, pH 7.4, 1% bovine serum albumin, 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD06798515 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | FITC conjugate |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | lyophilized powder |
species reactivity | mouse, human, rat |
technique(s) | flow cytometry: 0.5-5 μg/test using Jurkat T-cells western blot: 1:200-1:500 using rat brain membranes |
UniProt登记号 | P22001 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... KCNA3(3738) mouse ... Kcna3(16491) rat ... Kcna3(29731) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |