产品说明
一般描述
Phosphatidic acid (PA) has two fatty acids and one phosphate group attached to a glycerol backbone. The two fatty acids are present at position sn-1 and sn-2 of the C-atoms and the phosphate group is present in the sn-3 position of the C-atom.
应用
18:0 PA may be used:
- as a component in the bilayer to study its vesiculation ability on different coat protein I (COPI) fission factor
- to study its effects on intracellular Ca2+ concentration ([Ca2+]i) in C6 rat glioma and L2071 mouse fibroblast cells
- to study its effects on phosphorylation of cytochrome b(558) alpha chain (p22phox)
生化/生理作用
Phosphatidic acid (PA) acts as a biosynthetic precursor for the production of membrane glycerophospholipid and triacylglycerol. It participates in the modulation of mammalian target of rapamycin (mTOR) pathway. It may also participate in membrane trafficking, specifically in membrane fusion and fission.
包装
20 mL Clear Glass Screw Cap Vial (830865P-500mg)
5 mL Amber Glass Screw Cap Vial (830865P-25mg)
基本信息
经验(实验)分子式 | C39H76O8PNa |
分子量 | 726.98 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 25 mg (830865P-25mg) pkg of 1 × 500 mg (830865P-500mg) |
manufacturer/tradename | Avanti Polar Lipids 830865P |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |