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NEK6, active, GST tagged human

品牌
Sigma-Aldrich
货号
N9788
规格纯度
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
6484.55 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

NEK6 is a serine/threonine kinase that is a member of the Nek family of protein kinases that share an amino-terminal catalytic domain related to NIMA family. NEK6 is a nuclear and cytoplasmic kinase that is required for mitotic progression of human cells. NEK6 is phosphorylated and activated during M phase of the cell cycle.Inhibition of NEK6 function by either overexpression of an inactive NEK6 mutant or elimination of endogenous NEK6 by siRNA arrests cells in M phase and triggers apoptosis.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

质量水平200
重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity114-154 nmol/min·mg
分子量 ~63 kDa
UniProt登记号Q9HC98
运输dry ice
储存温度−70℃
Gene Informationhuman ... NEK6(10783)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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