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NIDA-41020

品牌
Sigma-Aldrich
CAS
502486-89-7
货号
N8162
规格纯度
≥97% (HPLC), solid
参考价格
9680.3 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

NIDA-41020 is a CB1 cannabinoid receptor antagonist. NIDA-41020 is structurally similar to Rimonabant, which is currently in clinical development. NIDA-41020 is less lipophilic; developed at NIDA as a potential radioligand for CB1 receptors, Ki = 4.1 nM [in comparison AM 251, AM 281, SR 141716 (Rimonabant) have Ki of 0.6, 4.5 and 1.8 nM respectively].

基本信息

经验(实验)分子式C23H24Cl2N4O2
分子量459.37
MDL编号MFCD08277026
PubChem化学物质编号329818682
NACRESNA.77

产品性质

质量水平100
测定≥97% (HPLC)
形式solid
颜色 off-white
溶解性DMSO: ~16 mg/mL
H2O: insoluble
储存温度2-8℃
SMILES stringCOc1ccc(cc1)-c2c(C)c(nn2-c3ccc(Cl)cc3Cl)C(=O)NN4CCCCC4
InChI1S/C23H24Cl2N4O2/c1-15-21(23(30)27-28-12-4-3-5-13-28)26-29(20-11-8-17(24)14-19(20)25)22(15)16-6-9-18(31-2)10-7-16/h6-11,14H,3-5,12-13H2,1-2H3,(H,27,30)
InChI keyKWDBQJRWPWTGPF-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H300 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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