产品说明
一般描述
Epidermal melanocytes are pigment-producing cells located at the basal level of epidermis, where they interact with keratinocytes via cellular processes called dendrites. Melanin, the pigment produced by melanocytes and responsible for skin color, is then transferred to keratinocytes, where it is stored in vesicles called melanosomes located around the nucleus to provide protection from UV radiation. HEM maintain their characteristic shape in culture for many generations. They produce melanin and serve as a useful cell model for the studies of melanocyte proliferation and differentiation, as well as progression of melanocytic neoplasia.
细胞系来源
Skin
应用
melanin production, melanocyte proliferation, differentiation
组分
Basal Medium containing 30% FBS & 10% DMSO
制备说明
- 3rd passage, >500,000 cells in Basal Medium containing 30% FBS & 10% DMSO
- Can be cultured at least 12 doublings
传代培养常规
Please refer to the HEM Culture Protocol.
基本信息
| NACRES | NA.81 |
产品性质
| 质量水平 | 100 |
| 生物来源 | human neonatal foreskin (normal) |
| 包装 | pkg of 500,000 cells |
| 生长模式 | Adherent |
| 核型 | 2n = 46 |
| 形态学 | Epidermal |
| technique(s) | cell culture | mammalian: suitable |
| 相关疾病 | metabolic disorders |
| 运输 | dry ice |
| 储存温度 | −196℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
