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Licochalcone-A, Synthetic-CAS 58749-22-7-Calbiochem

品牌
Sigma-Aldrich
CAS
58749-22-7
货号
435800
规格纯度
An estrogenic flavonoid with anti-tumor and antiparasitic properties.
参考价格
1123.01 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.
An estrogenic flavonoid with anti-tumor and antiparasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation, exhibits anti-tumor activity, and enhances the effect of Paclitaxel (Cat. No. 580555) and Vinblastine (Cat. No. 677175) chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

包装

10, 50 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Primary Target
Anti-tumor and antiparasitic properties
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Harmful (C)

制备说明

Further dilute 1:10 with aqueous buffer or medium just prior to use.

重悬

Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 6 months at -20°C.

其他说明

Rafi, M.M., et al. 2000. Anticancer Res. 20, 2653.
Zhai, L., et al. 1999. J. Antimicrob. Chemother. 43, 793.
Haraguchi, H., et al. 1998. Phytochemistry 48, 125.
Park, E.J., et al. 1998. Planta Med. 64, 464.
Chen, M., et al. 1994. Antimicrob. Agents Chemother. 38, 1470.
Chen, M., et al. 1993. Antimicrob. Agents. Chemother. 37, 2550.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C21H22O4
分子量338.40
MDL编号MFCD01417903

产品性质

质量水平100
测定≥96% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 yellow
溶解性DMSO: 10 mg/mL
ethanol: soluble
运输ambient
储存温度−20℃
InChI1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
InChI keyKAZSKMJFUPEHHW-DHZHZOJOSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 + H312 + H332
预防措施声明P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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