产品说明
一般描述
Circulating ghrelin is a multifunctional hormone secreted primarily by the stomach. Originally found as an endogenous ligand for the growth hormone secretagogue receptor, it is also an appetite-stimulating hormone in the regulation of energy homeostasis. It consists of 28 amino acids and the n-octanoylation of serine-3 position is necessary for its bioactivity. Long considered a key player in obesity, ghrelin may also play a role in maintaining the balance between insulin and glucose and the development of diabetes. The spike in insulin secretion occurring after eating usually correlates with a dip in ghrelin production. Researchers determined that in rat models of uncontrolled diabetes, food intake still suppressed ghrelin concentrations in the blood, but only approximately half as effectively as when insulin was present.
Millipore is pleased to offer a new Rat/Mouse Ghrelin (Active) ELISA kit for the quantification of active ghrelin in rat and mouse serum or plasma samples. Each kit is sufficient to measure 39 unknown samples in duplicate.
特异性
Rat/Mouse Ghrelin (Active) - 100%
Rat/Mouse "Des-Octanoyl" Ghrelin - 0%
Canine Ghrelin (Active) - 111%
Porcine Ghrelin (Active) - 98%
应用
Used to detect/quantify: Ghrelin
其他说明
Please contact Technical Service for linearity of dilution.
免责声明
For research use only. Not for use in diagnostic procedures.
基本信息
| eCl@ss | 32161000 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 100 |
| species reactivity | mouse, rat |
| technique(s) | ELISA: suitable |
| UniProt登记号 | Q9EQX0 (mouse) Q9QYH7 (rat) Q9UBU3 |
| assay range | inter-assay cv: 1-10% intra-assay cv: 0.3-7% (Serum) inter-assay cv: 1-5% intra-assay cv: 1-6% (Plasma) |
| detection method | colorimetric fluorometric |
安全信息
| 象形图 |    |
| 警示用语： | Danger |
| 危险声明 | H290 - H302 + H332 - H311 - H315 - H317 - H319 - H335 - H411 |
| 预防措施声明 | P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
