产品说明
应用
Interleukin-2 human has been used to assess changes in tumor necrosis factor receptor 1 (TNFR1). It has also been used in TNFR2 expression on Tregs.
生化/生理作用
Interleukin 2 (IL2) is a pro-inflammatory cytokine. It consists of three subunits, in which the β subunit is important for receptor mediated signaling. IL2 enhances the development of T regulatory cells and plays a crucial role in antitumor immunity.
白细胞介素-2(IL-2)是由某些T淋巴细胞亚群产生的免疫调节因子。该淋巴因子能够促进活化T细胞和相关细胞类型的长期生长。IL-2在NK细胞的激活和增殖、诱导γ-干扰素和B细胞生长因子分泌中发挥作用，并且能够调节IL-2受体的表达。
外形
Lyophilized from a 0.2 μm filtered solution in 50 mM sodium phosphate buffer, pH 7.0, containing 0.1% human serum albumin per 0.1 mL of cytokine.
分析说明
The biological activity is tested in a cell proliferation assay using an IL-2 dependent murine cytotoxic T cell line, CTLL-2.
基本信息
| MDL编号 | MFCD00165721 |
| NACRES | NA.75 |
产品性质
| 质量水平 | 200 |
| 生物来源 | human |
| 重组 | expressed in Pichia pastoris |
| 测定 | ≥98% (SDS-PAGE and HPLC) |
| 形式 | lyophilized powder |
| 分子量 | predicted mol wt ~15 kDa |
| 包装 | pkg of 10KU |
| technique(s) | cell culture | mammalian: suitable |
| 杂质 | endotoxin, tested |
| web metadata keyword.default | TCGF |
| UniProt登记号 | P60568 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IL2(3558) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
