产品说明
应用
Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems.
生化/生理作用
α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS).
基本信息
经验(实验)分子式 | C11H12N2O2 · HCl |
分子量 | 240.69 |
MDL编号 | MFCD00069293 |
PubChem化学物质编号 | 24278493 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
溶解性 | H2O: 50 mg/mL |
SMILES string | Cl.C1CN=C(N1)C2COc3ccccc3O2 |
InChI | 1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H |
InChI key | MYUBYOVCLMEAOH-UHFFFAOYSA-N |
Gene Information | human ... ADRA2A(150), ADRA2B(151), ADRA2C(152) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P301 + P310 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |