产品说明
一般描述
Idebenone is a short-chain benzoquinone drug.
应用
Idebenone has been used:
- to treat mutant myocilin (mMYOC) cells for drug treatment assay
- to validate C2C12 secondary cell screening assay
- to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs
包装
25 mg in glass insert
100 mg in poly bottle
生化/生理作用
Idebenone is used in the treatment of visual impairment in adolescents and adults with Leber′s hereditary optic neuropathy (LHON). It serves as an antioxidant. It helps to guard the heart muscle against oxidative stress.
一种短链辅酶 Q 类似物,可通过介导电子从 N2 转移到氧来增强超氧化物的形成。
基本信息
经验(实验)分子式 | C19H30O5 |
分子量 | 338.44 |
MDL编号 | MFCD00274552 |
PubChem化学物质编号 | 329815386 |
产品性质
质量水平 | 200 |
测定 | ≥98% (HPLC) |
形式 | powder |
溶解性 | methanol: 50 mg/mL, clear to slightly hazy |
储存温度 | room temp |
SMILES string | O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O |
InChI | 1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3 |
InChI key | JGPMMRGNQUBGND-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |