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Anti-Hepatocyte Growth Factor Receptor antibody produced in goat

品牌
Sigma-Aldrich
货号
H9911
规格纯度
lyophilized powder, affinity isolated antibody
参考价格
4692 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Blockade of receptor-ligand interaction: In a functional ELISA, 0.3-1 μg/mL of this antibody will block 50% of the binding of 5 ng/mL of Recombinant Human HGF to immobilized Recombinant Mouse HGF R/cMET Fc Chimera coated at 1 μg/mL (100 μL/well). At 20 μg/mL, this antibody will block >90% of the binding.

免疫原

purified recombinant mouse hepatocyte growth factor receptor extracellular domain expressed in insect Sf 21 cells.

生化/生理作用

Hepatocyte Growth Factor (HGF) is a multifunctional, heparin-binding factor that stimulates the proliferation of liver cells. The cellular effects of HGF are mediated by its receptor, c-Met, that leads to significant activation of ERK, Src/FAK, STAT3 and PI3K signaling. Various functions of the HGF/c-Met signaling include proliferation, cell survival, motility, adhesion and tissue regeneration. Apart from liver, HGF also mediates regeneration of kidney, lung and gastro-intestines.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (pH 7.4) with 5% trehalose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD03791598
NACRESNA.41

产品性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivitymouse
technique(s)immunohistochemistry: 5-15 μg/mL using using cells and tissue
western blot: 0.1-0.2 μg/mL
UniProt登记号P16056
储存温度−20℃
Gene Informationmouse ... Met(17295)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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