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Anti-phospho-Growth Associated Protein-43 (pSer41) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
G8043
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
4330.86 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

synthetic phosphopeptide derived from the region of rat GAP-43 phosphorylated on serine 41.

应用

Anti-phospho-Growth Associated Protein-43 (pSer41) antibody produced in rabbit is suitable for immunoblotting at a working dilution of 1:1000.

生化/生理作用

GAP-43 is an intracellular phosphoprotein that is present exclusively in the peripheral and central nervous systems. Protein kinase C (PKC) phosphorylates GAP-43 on a single site, serine 41. This phosphorylated protein is found in the areas where growth cones make productive and stable contacts with other cells. It facilitates stabilization of long actin filaments. Phosphorylation by PKC at serine 41 is related to nerve-terminal sprouting and long-term potentiation as high levels of GAP-43 are present in neocortical areas and in the limbic system. It is crucial in mediating experience dependent plasticity.

外形

Solution in 10 mM HEPES, pH 7.5, containing 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.

分析说明

An additional band at 150-160 kDa may be detected and reflects the oligomeric nature of GAP-43.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD03791562
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 43 kDa
species reactivityrat, human, mouse
technique(s)western blot: 1:1,000
UniProt登记号P17677
运输dry ice
储存温度−20℃
Gene Informationhuman ... GAP43(2596)
mouse ... Gap43(14432)
rat ... Gap43(29423)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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