产品说明
免疫原
Recombinant regulator of G-protein signalling 19 interacting protein 1 isoform 1
Immunogen Sequence: GI # 5031715, sequence 1-333
应用
Anti-GIPC1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
GIPC PDZ domain containing family, member 1 (GIPC1) is a protein encoded by the GIPC1 gene in humans. The mammalian GIPC1 consists of a central PDZ domain and a C-terminal acyl carrier protein (ACP) domain. It is an essential adaptor protein of receptors that plays an important role in cancer progression and therapy resistance. The GIPC1 cytoplasmic scaffold protein interacts with numerous receptor signaling complexes and plays a role in tumorigenesis. It is highly expressed in a number of human malignancies that include breast, ovarian, gastric and pancreatic cancers. GIPC1 inhibition may be a new target for therapeutic development for the treatment of human cancers. It is a breast cancer-associated immunogenic antigen that is overexpressed in breast cancer.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | chicken |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human, mouse, rat |
| manufacturer/tradename | Genway 15-288-22308F |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_005707.1 |
| UniProt登记号 | O14908 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GIPC1(10755) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
