产品说明
免疫原
peptide corresponding to the human FBG3 protein (amino acids 103-119). This sequence has 94% homology with mouse and rat.
应用
Anti-FBG3 (FBXO44) antibody is suitable for western blot: 1:500-1:1,000.
生化/生理作用
F-box protein, is the critical component of conserved ubiquitin–protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box) and acts as a substrate recognition component of the ubiquitin ligase complex SCF (Skp-Cullin-F-box). It is expressed in human tissues including kidney, liver, brain and muscle tissues. It is associated with various critical biological processes such as in regulating the cell cycle, immune response, signaling cascades and developmental programs. The proteins have a bipartite structure and the core complex, whereas divergent protein-protein interaction motifs selectively bind their cognate substrates.
外形
Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
基本信息
| MDL编号 | MFCD08705455 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~30 kDa by calculation |
| species reactivity | human |
| technique(s) | western blot: 1:500-1:1,000 |
| UniProt登记号 | Q9H4M3 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FBXO44(93611) mouse ... Fbxo44(230903) rat ... Fbxo44(500587) |
