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Anti-S1P4, C-Terminal antibody produced in rabbit

品牌
Sigma-Aldrich
货号
E7653
规格纯度
~1 mg/mL, fractionated antiserum, buffered aqueous solution
参考价格
4330.86 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

synthetic peptide (approximately 2.5 kDa, native) derived from the C-terminal region of the EDG-6/S1P4 receptor.

应用

Anti-S1P4, C-Terminal antibody produced in rabbit is suitable for western blotting at a working concentration of 5 to 10 μg/ml using COS cells transfected with full length EDG-6.

生化/生理作用

Sphingosine-1-phosphate receptor 4 (S1PR4, EDG-6) is a human gene which encodes a G protein-coupled receptor and is identified as an orphan G-protein-coupled receptor. It binds the lipid signaling molecule sphingosine 1-phosphate (S1P). EDG-6 is a member of the endothelial differentiation gene (EDG) G protein-coupled receptor family. It is expressed in lymphoid, hematopoietic tissue and in the lung. EDG-6 acts as a high affinity receptor for SPP that couples to a G(i/o) protein leading to the activation of growth-related signaling pathways. It is one of the S1P or lysosphingolipid receptors that couples to phospholipase C-Ca2+ system through pertussis toxin-sensitive G-proteins.

外形

Supplied in phosphate buffered saline, pH 7.3, and 0.08% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD03454969
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式fractionated antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~45 kDa by SDS-PAGE
species reactivityhuman
浓度~1 mg/mL
technique(s)western blot: suitable
UniProt登记号O95977
运输wet ice
储存温度−20℃
Gene Informationhuman ... S1PR4(8698)

Sigma-Aldrich

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