产品说明
生化/生理作用
Chaperonin60 (GroEL) and chaperonin10 (GroES) belong to the ubiquitous family of heat-shock molecular chaperones found in prokaryotes and in eukaryotic organelles. The chaperonins assist the folding of nascent, organelle-imported or stress-destabilized polypeptides. In vitro, purified GroEL together with purified GroES in the presence of Mg-ATP facilitate refolding and reactivation of denatured proteins, e.g., the photosynthetic enzyme rubisco and the mitochondrial enzyme rhodanese.
The folding activity of a 1:1 molar mixture of GroEL and GroES was tested using urea-denatured rhodanese. At least 2-fold reactivation of rhodanese over the spontaneous reactivation was obtained.
包装
Package size based on protein content.
外形
Lyophilized powder containing Tris buffer salts, potassium chloride, dithiothreitol and trehalose as stabilizer.
基本信息
| MDL编号 | MFCD00163256 |
| NACRES | NA.32 |
产品性质
| 生物来源 | Escherichia coli |
| 质量水平 | 200 |
| 重组 | expressed in E. coli overproducing strain |
| 测定 | ≥95.0% (SDS-PAGE) |
| 形式 | lyophilized powder |
| UniProt登记号 | P61604 |
| 储存温度 | 2-8℃ |
| Gene Information | human ... HSPE1(3336) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
