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Anti-Caveolin-2 antibody produced in rabbit

Anti-Caveolin-2 兔抗

品牌
Sigma-Aldrich
货号
C9992
规格纯度
~1 mg/mL, affinity isolated antibody, buffered aqueous solution, suitable for western blot: 1 μg/mL
参考价格
5705.99 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Caveolin-2 is an isoform of caveolin, an integral transmembrane protein of the caveolae membranes. It has a molar mass of 20-22 kDa and is a major coat protein found in caveolae of most cell types. It exists as two isoforms α and β due to alternative splicing of the respective mRNAs. Caveolin-2α corresponds to the full-length protein (20 kDa, 162 amino acids), whereas caveolin-2β isoform lacks a 13 amino acid sequence at its N-terminus.

免疫原

synthetic peptide corresponding to amino acids 1-20 located at the N-terminus of mouse caveolin-2, conjugated to KLH. This sequece is identical in rat caveolin-2, highly conserved (90% identity) in human, dog, and pig caveolin-2, and is not found in caveolin-1 and caveolin-3.

生化/生理作用

Caveolin-2 colocalizes and forms a hetero-oligomeric complex with caveolin-1 in vivo. Caveolins family members function as scaffolding proteins to organize and concentrate specific lipids such as cholesterol and glycosylphosphatidylinositol (GPI) and lipid modified signaling molecules within caveolae membranes. Caveolin-2 is phosphorylated on Ser23 and Ser36 and modulates caveolin-1-dependent caveola formation.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01633098
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~20 kDa
species reactivitypig (predicted), rat, canine, human (predicted), mouse
浓度~1 mg/mL
technique(s)indirect immunofluorescence: suitable
western blot: 1-2 μg/mL using whole extract of mouse 3T3-L1 adipocytes or rat kidney NRK cells
UniProt登记号P51636
运输dry ice
储存温度−20℃
Gene Informationhuman ... CAV2(858)
mouse ... Cav2(12390)
rat ... Cav2(363425)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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