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CDK1/Cyclin A2, active, GST tagged human

CDK1/细胞周期蛋白 A2,活性,GST 标记 人

品牌
Sigma-Aldrich
货号
C0244
规格纯度
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
6484.55 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

质量水平200
重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity151-205 nmol/min·mg
分子量CDK1 subunit ~59 kDa
cyclin A2 ~78 kDa
UniProt登记号P06493
P20248
运输dry ice
储存温度−70℃
Gene Informationhuman ... CCNA2(890), CDK1(983)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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