产品介绍：
产品说明
应用
Cromakalim has been used:
- as a potassium channel agonist to study its response to an acute increase in downstream pressure in rat lymphatic vessels.
- as a potassium channel opener to study its effects on the release of transmitters from adrenergic nerves in rat vas deferens.
- as a potassium channel activator to study its effects on the release of transmitters from purinergic and cholinergic nerves in the rat detrusor muscle.
包装
10, 50 mg in glass bottle
生化/生理作用
Cromakalim is an activator of the potassium channel. It is involved in the relaxation of the vascular smooth muscles. Cromakalim exhibits anti-hypertensive activity.
特点和优势
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C16H18N2O3 |
| 分子量 | 286.33 |
| MDL编号 | MFCD00133201 |
| PubChem化学物质编号 | 24891962 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 储存温度 | 2-8℃ |
| SMILES string | CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N3CCCC3=O)C#N |
| InChI | 1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3/t14-,15+/m1/s1 |
| InChI key | TVZCRIROJQEVOT-CABCVRRESA-N |
| Gene Information | rat ... Kcna1(24520), Kcnj1(24521), Kcnj5(29713), Kcnj8(25472) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
