产品介绍：
产品说明
一般描述
CX546, a benzoylpiperidine derivative ampakine is an analog of CX516.
应用
CX546 has been used as positive allosteric modulator for the glutamatergic receptor α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) in mice.
包装
10, 50 mg in glass bottle
生化/生理作用
CX546 has antipsychotic functionality and has the potential to treat schizophrenia. It improves the defects associated with the prepulse inhibition (PPI) and latent inhibition (LI) in mice lacking metabotropic glutamate receptor type 5 (mGluR5). Additionally, CX546 potentiates synaptic plasticity, elicits neuroprotection and promotes the neurotrophin expression.
Positive AMPA glutamate receptor modulator.
注意
Photosensitive
基本信息
| 经验(实验)分子式 | C14H17NO3 |
| 分子量 | 247.29 |
| MDL编号 | MFCD01860868 |
| PubChem化学物质编号 | 24277960 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 储存条件 | protect from light |
| 颜色 | white to off-white |
| 溶解性 | DMSO: ≥10 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | O=C(N1CCCCC1)c2ccc3OCCOc3c2 |
| InChI | 1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2 |
| InChI key | LJUNPHMOGNFFOS-UHFFFAOYSA-N |
| Gene Information | human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
