产品说明
一般描述
BM(PEG)2 and BM(PEG)3 are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e. oligomerization) or protein interactions. Because BM(PEG)2 and BM(PEG)3 have the same reactivity but differ in length, the relative success of these and similar reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.
特点和优势
- Reactive groups: maleimide (both ends)
- Reactive towards: sulfhydryl groups
- Long, pegylated, sulfhydryl-to-sulfhydryl crosslinkers, composed of maleimide groups and 2-unit polyethylene glycol spacer arm
- PEG spacers provide unique advantages, including enhanced solubility, increased stability, reduced tendency toward aggregation and reduced immunogenicity
- Pure compounds with defined structure and molecular weight, ensuring reproducible protein-modification effects
- Ideal for small molecule or peptide conjugations
注意
This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
基本信息
| 经验(实验)分子式 | C14H16N2O6 |
| 分子量 | 308.29 |
| MDL编号 | MFCD01096749 |
| PubChem化学物质编号 | 329768819 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥90% |
| 形式 | powder |
| 分子量 | 308.29 |
| reaction suitability | reagent type: cross-linking reagent |
| 储存条件 | desiccated |
| 溶解性 | water: soluble |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
| SMILES string | O=C(C=CC1=O)N1CCOCCOCCN2C(C=CC2=O)=O |
| InChI | 1S/C14H16N2O6/c17-11-1-2-12(18)15(11)5-7-21-9-10-22-8-6-16-13(19)3-4-14(16)20/h1-4H,5-10H2 |
| InChI key | FERLGYOHRKHQJP-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
