产品说明
包装
50 mg in glass bottle
生化/生理作用
Methazolamide has a plasma half-life of 14 hours in humans. Methazolamide has relatively good lipid solubility and low plasma protein binding ability. Thus, it diffuses into tissues and fluids much more readily than acetazolamide, another carbonic anhydrase inhibitor. Methazolamide has less side effects than acetazolamide.
Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models.
其他说明
Light sensitive
基本信息
经验(实验)分子式 | C5H8N4O3S2 |
分子量 | 236.27 |
EC 号 | 209-066-7 |
MDL编号 | MFCD00083416 |
PubChem化学物质编号 | 329825590 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | protect from light |
颜色 | white to beige |
mp | 208 ℃ (dec.) (lit.) |
溶解性 | DMSO: 20 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O |
InChI | 1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+ |
InChI key | FLOSMHQXBMRNHR-QPJJXVBHSA-N |
Gene Information | human ... CA1(759), CA2(760), CA4(762), CA7(766) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 + H312 + H332 - H351 |
预防措施声明 | P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313 |
危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |